Effects: Nourishes yin and drains fire, relieves vexation and calms the spirit.
Core pathomechanism: A Shaoyin disease pattern of yin deficiency with effulgent fire and disharmony between the Heart and Kidney. Kidney water is deficient below and cannot rise to assist Heart fire; Heart fire is hyperactive above and cannot descend to communicate with the Kidney. As a result, Heart fire becomes solitarily hyperactive and disturbs the spirit.
2. When it is used
This formula is simple in composition and focused in action, combining clearing and tonifying methods. Together the herbs nourish yin, drain fire, and restore communication between the Heart and Kidney.
3. Pattern and presentation
Main symptoms:
Vexation in the chest with inability to lie down and sleep: unusual restlessness and inability to fall asleep, a typical manifestation of yin deficiency with effulgent fire disturbing the spirit.
General and accompanying symptoms:
o Dry mouth and throat, heat in the palms and soles.
o Red tongue with little coating, or crimson tongue with no coating.
o Thin, rapid pulse.
4. Tongue and pulse
Tongue: Crimson-red tongue body, scant fluid, little or no coating.
Pulse: Thin and rapid, or deep, thin and rapid.
5. Common modifications
For marked yin deficiency with pronounced dry mouth: add Mai Dong (ophiopogon tuber), Sha Shen (glehnia root/adenophora root), and Sheng Di (fresh rehmannia root) to strengthen yin nourishment.
For severe insomnia: add Suan Zao Ren (spiny jujube seed), Bai Zi Ren (arborvitae seed), and Long Gu (dragon bone) to heavily settle and calm the spirit.
For accompanying tidal fever and night sweats: add Di Gu Pi (wolfberry root bark) and Bai Wei (cynanchum root) to clear deficiency heat.
Modern applications: This formula is widely used for neurasthenia, anxiety disorder, menopausal syndrome, and hyperthyroidism where the pattern is yin deficiency with effulgent fire.
6. Cautions and clinical notes
Contraindications:
o Contraindicated in those with Spleen-Stomach yang deficiency-cold and loose stools. The herbs in this formula are mostly cold, cooling, and cloying, and can readily damage the Spleen and Stomach.
o Contraindicated in cases of externally contracted fever.
o The egg yolk in the formula is used raw; attention should be paid to the hygiene of its source.
7. Granule conversion and dose
Calculation of the total raw herb weight of the original formula (excluding egg yolk):
o Huang Lian (coptis rhizome) 12g + Huang Qin (scutellaria root) 6g + Bai Shao (white peony root) 6g + E Jiao (donkey-hide gelatin) 9g = 33 g.
Conversion to 5:1 granules:
o 33 g raw herb ÷ 5 = 6.6 g granules.
Recommended dose and special method of administration:
o Special method for taking with dissolved egg yolk: Take 7 g of granules, add hot water, and once the temperature of the liquid has cooled to warm (below about 40°C), stir in 2 fresh egg yolks. Mix well and take in 3 divided doses over the course of one day.
o 特殊冲服方法:取7克颗粒剂,加入热水,待药液温度降至温热(约40℃以下)时,搅入2枚新鲜鸡子黄(蛋黄),搅拌均匀后一天分三次服用。
英文
中文
拼音
%
Golden Thread
黄连
Huang Lian
4.12%
Baical Skullcap Root
黄芩
Huang Qin
6.19%
White Peony Root
白芍
Bai Shao
12.37%
Donkey-Hide Glue
阿胶
E Jiao
9.28%
Rehmannia Root
地黄(生)
Di Huang (Sheng)
37.11%
Yolk
鸡子黄
Ji Zi Huang
30.93%
Take 7 g of granules, add hot water, and once the liquid has cooled to warm, stir in 2 egg yolks. Mix well and take in 3 divided doses over the course of one day.